"Therapeutic massage reduced stress in various clinicalsituations such as that of depression, pain syndromes andauto-immune diseases.20These parameters were assayedwith the measurement of substances like cortisol, serotoninand dopamine. In a study with elderly subjects, it wasobserved that foot massage (reflexotherapy) improvedquality of sleep, reduced depression and increased thelevel of serotonin.21With the same technique, a signifi-cant difference was also observed in climacteric symp-toms, in fatigue, in total cholesterol and in the level of cortisol."